effects of exercise on cardiovascular performance in the elderly
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ID: 161090
2014
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Abstract
Progressive Aging induces several structural and functional alterations in the cardiovascular system, among whom particularly important are a reduced number of myocardial cell and of increased interstitial collagen fibers, which result in impaired LV diastolic function. Even in the absence of cardiovascular disease, aging is strongly associated to a age-related reduced maximal aerobic capacity. This is due to a variety of physiological changes both at central and at peripheral level; among central factors, a reduced maximal heart rate (HR) response to exercise due to beta1 receptors down-regulation plays a major role; among peripheral factors, progressive aging is associated to peripheral muscle cell biochemical and functional changes including reduction of skeletal muscle cells, decrease of Myosin Heavy Chain (MHC) I and IIa muscle fibers and impaired muscle oxidative capacity
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| Reference Key |
evigorito2014frontierseffects
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|---|---|
| Authors | ;Carlo eVigorito;Francesco eGiallauria;Francesco eGiallauria |
| Journal | Journal of clinical and experimental dentistry |
| Year | 2014 |
| DOI |
10.3389/fphys.2014.00051
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| URL | |
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