bio-prospecting of a few brown seaweeds for their cytotoxic and antioxidant activities

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ID: 160970
2011
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Abstract
Methanolic extracts (MEs) of seven brown seaweeds occurring in the Indian coastal waters were screened for their cytotoxic and antioxidant properties following various assays. The methanolic extracts of seaweeds in the order of Dictyopteris australis > Spatoglossum variabile > Stoechospermum marginatum > Spatoglossum aspermum showed significant cytotoxic activity. A very high DPPH radical scavenging activity was exhibited by the methanolic extracts prepared from St. marginatum, Padina tetrastromatica, Dictyopteris delicatula and S. aspermum. The total phenolic content of the MEs varied from 13.19 ± 0.32 to 25.29 ± 0.445 gallic acid equivalents (mg g−1 of methanolic extract). The reducing power assay indicated a dose dependency, at concentrations of 0.1, 0.5 and 1.0 and 2.0 mg mL−1 of MEs and decreased in the following order: Butylated hydroxy toluene > P. tetrastromatica > D. delicatula > S. aspermum > S. variabile > S. marginatum > D. australis > S. marginatum. Furthermore, D. australis, S. aspermum, S. variabile and S. marginatum demonstrated good metal ion chelating properties. All the above evidences suggest that, the antioxidant compounds found in brown seaweeds scavenge free radicals through effective intervention. This decisively promotes them as a potential source of natural antioxidants.
Reference Key
vinayak2011evidence-basedbio-prospecting Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Rashmi C. Vinayak;A. S. Sabu;Anil Chatterji
Journal ACS applied materials & interfaces
Year 2011
DOI
10.1093/ecam/neq024
URL
http://dx.doi.org/10.1093/ecam/neq024
Keywords
Other systems of medicine

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