toxicological aspects and occurrence of patulin in apple juice/
aspectos toxicológicos e ocorrência de patulina em suco de maçã

Clicks: 165
ID: 160762
2005
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Abstract
Patulin is a secondary metabolite produced by different species of fungi, being Penicillium expansum the most important species. Patulin is a mycotoxin that has been found mainly in mature apples used in the production of concentrated apple juice, but it can also be in other fruits, vegetables and nutritious products. Experiments carried out with laboratory animals have demonstrated that this mycotoxin produces several harmful effects, including mutagenicity, teratogenicity, carcinogenicity, immunosuppression and acute intoxications characterized by pulmonary oedema, hemorrhages, damages in the capillaries of liver, spleen and kidneys, as well as cerebral oedema. This revision article approaches physicochemical properties and toxicological aspects of the patulin, as well as its occurrence and strategies to prevent its presence in apple juices.

A patulina é um metabólito secundário produzido por diferentes gêneros e espécies de fungos. Penicillium expansum é certamente a espécie mais importante. É uma micotoxina encontrada principalmente em maçãs maduras utilizadas na produção de suco de maçã concentrado, mas também pode estar presente em outras frutas, vegetais e produtos alimentícios. Experimentos em animais de laboratório demonstraram que esta micotoxina produz diversos efeitos nocivos, incluindo mutagenicidade, teratogenicidade, carcinogenicidade, imunossupressão e intoxicações agudas caracterizadas por edema pulmonar, hemorragias, danos nos capilares hepáticos, do baço e rins, bem como edema cerebral. O presente artigo de revisão aborda aspectos físico-químicos e toxicológicos da patulina, bem como a sua ocorrência e estratégias para prevenir a sua presença em sucos de maçã.

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junior2005semina:toxicological Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Miguel Machinski Junior;Rubia Andreia Falleiros de Pádua
Journal frontiers in neuroendocrinology
Year 2005
DOI
10.5433/1679-0359.2005v26n4p535
URL
http://www.uel.br/revistas/uel/index.php/semagrarias/article/view/2375
Keywords
Agriculture (General) patulina

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