synthesis of [(4-chloro-5h-1,2,3-dithiazol-5-ylidene)amino]azines

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ID: 160225
2011
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Abstract
The reactions of 2-, 3- and 4-aminopyridines with 4,5-dichloro-1,2,3-dithiazol-ium chloride (Appel salt) 4 to give N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)pyridin-X-amines 1a (X = 2), 1g (X = 3) and 1k (X = 4) were optimized with respect to base, temperature and reaction time. Based on these conditions a total of thirteen [(dithiazol-ylidene)amino]azines 1a-m were prepared and fully characterized.
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Authors ;Panayiotis A. Koutentis;Maria Koyioni;Sophia S. Michaelidou
Journal Journal of ethnopharmacology
Year 2011
DOI
10.3390/molecules16118992
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