prognosis of multifocal papillary thyroid carcinoma
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2013
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Abstract
This study was to investigate the clinical features and therapeutic outcomes of multifocal papillary thyroid microcarcinoma (PTMC). A total of 2,418 papillary thyroid carcinoma (PTC) patients had undergone thyroidectomy in one medical center between 1977 and 2010. There were 483 (20.0%) diagnosed with multifocal PTC. The percentage of multifocal PTC was higher in PTMC patients (22.0%) than in non-PTMC patients (19.5%). Demographic and clinical characteristics of PTMC and multifocal PTC in PTC patients were traced. Multifocal PTC patients presented with smaller tumors at an older age, and a higher percentage underwent total or complete thyroidectomy. These patients also showed a higher incidence of postoperative disease progression than did unifocal PTC patients. Comparison of 483 patients with multifocal PTMC and non-PTMC tumors showed a higher incidence of postoperative disease progression in patients with non-PTMC; otherwise, there was no statistical difference in disease-specific and total mortality between these two groups. In conclusion, the incidence of multifocal PTMC was not lower than that of non-PTMC, and postoperative therapies were necessary for both multifocal PTMC and non-PTMC patients.
| Reference Key |
kuo2013internationalprognosis
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|---|---|
| Authors | ;Sheng-Fong Kuo;Shu-Fu Lin;Tzu-Chieh Chao;Chuen Hsueh;Kun-Ju Lin;Jen-Der Lin |
| Journal | zhonghua wei zhong bing ji jiu yi xue |
| Year | 2013 |
| DOI |
10.1155/2013/809382
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| URL | |
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