performance of a new hpv cervi-collect collection and transportation kit

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2012
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Abstract
Background. Liquid-based Pap (L-Pap) media are used for Pap and human papillomavirus (HPV) testing. Objectives. To compare RealTime High Risk (HR) HPV testing of a new collection kit (Cervi-Collect) and PreservCyt L-Pap specimens. To determine ease of use and safety of Cervi-Collect. Methods. L-Pap samples (n=203) were tested with HC2 and RealTime HR HPV and Cervi-Collect with RealTime HR HPV. Discordant samples were genotyped. Results. L-Pap and Cervi-Collect specimens tested by RealTime HR HPV showed 93.1% agreement (Kappa 0.86). RealTime HR HPV and HC2 on L-Pap had 90.3% agreement (Kappa 0.80). RealTime HR HPV on Cervi-Collect and HC2 on L-Pap showed 88.2% agreement (Kappa 0.76). Sixteen of 21 samples which were HC2 negative and RealTime HR HPV positive on L-Pap or Cervi-Collect contained HR HPV genotypes. Eleven healthcare collectors were in strong agreement on a usability and safety questionnaire. Conclusion. Cervi-Collect samples were easy to collect and showed strong agreement with L-Pap samples tested with RealTime HR HPV or HC2.
Reference Key
chernesky2012journalperformance Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors M. Chernesky, S. Huang, D. Jang, B. Erickson, J. Salituro, H. Engel, J. Gilchrist, P. Neuscheler, W. B. Mak, K. Abravaya
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Journal joule
Year 2012
DOI
10.1155/2012/503432
URL
http://dx.doi.org/10.1155/2012/503432
Keywords
neoplasms Oncology including cancer and carcinogens tumors

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