integrated synthesis of nucleotide and nucleosides influenced by amino acids

Clicks: 237
ID: 158480
2019
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Abstract
The direct glycosylation of ribose by nucleobases offers an intuitive route to nucleosides, but is known to be challenging under prebiotically plausible reaction conditions. Here, the addition of amino acids is shown to influence the product distribution, and a dynamic exchange of nucleobases between nucleosides and nucleotides is observed.
Reference Key
surez-marina2019communicationsintegrated Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Irene Suárez-Marina;Yousef M. Abul-Haija;Rebecca Turk-MacLeod;Piotr S. Gromski;Geoffrey J. T. Cooper;Andrea Olivé Olivé;Stephanie Colón-Santos;Leroy Cronin
Journal prostate cancer and prostatic diseases
Year 2019
DOI
10.1038/s42004-019-0130-7
URL
http://link.springer.com/article/10.1038/s42004-019-0130-7
Keywords
chemistry

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