integrated synthesis of nucleotide and nucleosides influenced by amino acids
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ID: 158480
2019
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Abstract
The direct glycosylation of ribose by nucleobases offers an intuitive route to nucleosides, but is known to be challenging under prebiotically plausible reaction conditions. Here, the addition of amino acids is shown to influence the product distribution, and a dynamic exchange of nucleobases between nucleosides and nucleotides is observed.
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surez-marina2019communicationsintegrated
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| Authors | ;Irene Suárez-Marina;Yousef M. Abul-Haija;Rebecca Turk-MacLeod;Piotr S. Gromski;Geoffrey J. T. Cooper;Andrea Olivé Olivé;Stephanie Colón-Santos;Leroy Cronin |
| Journal | prostate cancer and prostatic diseases |
| Year | 2019 |
| DOI |
10.1038/s42004-019-0130-7
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