the cross-bridge of skeletal muscle is not synchronized either by length or force step
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2015
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Abstract
Force and length steps, applied to a muscle fiber in the isometric state, are believed to synchronize attached cross-bridges. This alleged synchronization facilitates the interpretation of the experiments. A rapid force step elicits an elastic response of the attached cross-bridges, followed by an isotonic phase. The decay of this second isotonic phase is of the first order. This excludes that the attached cross-bridges may decay all at the same time. The change of the X-ray interference distance during the second phase measures the stroke size only in the unrealistic case that the cross-bridges are and remain all attached. A rapid force step does not synchronize attached cross-bridges. The change of X-ray interference during the second phase does not measure the stroke size. These conclusions significantly change the picture of the mechanism of skeletal muscle contraction.
| Reference Key |
grazi2015internationalthe
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| Authors | ;Enrico Grazi |
| Journal | Intertax |
| Year | 2015 |
| DOI |
10.3390/ijms160612064
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| URL | |
| Keywords | Keywords not found |
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