Paramyxo- and Coronaviruses in Rwandan Bats.

Clicks: 403
ID: 15470
2019
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Abstract
A high diversity of corona- and paramyxoviruses have been detected in different bat species at study sites worldwide, including Africa, however no biosurveillance studies from Rwanda have been reported. In this study, samples from bats collected from caves in Ruhengeri, Rwanda, were tested for the presence of corona- and paramyxoviral RNA using reverse transcription PCR assays. Positive results were further characterized by DNA sequencing and phylogenetic analysis. In addition to morphological identification of bat species, we also did molecular confirmation of species identities, contributing to the known genetic database available for African bat species. We detected a novel in two Geoffroy's horseshoe bats () bats. We also detected several different paramyxoviral species from various insectivorous bats. One of these viral species was found to be homologous to the genomes of viruses belonging to the genus. Additionally, a -related sequence was detected in an Egyptian rousette fruit bat (). These results expand on the known diversity of corona- and paramyxoviruses and their geographical distribution in Africa.
Reference Key
markotter2019paramyxotropical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Markotter, Wanda;Geldenhuys, Marike;Jansen van Vuren, Petrus;Kemp, Alan;Mortlock, Marinda;Mudakikwa, Antoine;Nel, Louis;Nziza, Julius;Paweska, Janusz;Weyer, Jacqueline;
Journal Tropical medicine and infectious disease
Year 2019
DOI
E99
URL
https://www.mdpi.com/2414-6366/4/3/99
Keywords
resveratrol extracellular matrix elt-3-luc xenograft model uterine fibroids neuroimmunology neurodevelopmental disorders non-invasive brain stimulation demyelinating disease sca2 cerebellar ataxy strock neurodegenerative disorders neuroimmunomodulation immune response lymph node differential expression iav-s pcv-2 prrsv

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