synthetic analogue of stilbene containing an imidazole nucleus
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ID: 153524
2000
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Abstract
Synthesis of trans-1,2-bis(4-nitro-1-p-methoxybenzylimidazol-5-yl)ethene (1) as an imidazole analogue of stilbene has been reported. In order to confirm the trans geometry of the product using an UV spectral comparison, a mixture of both trans (1) and cis isomer (3) was also prepared. The synthesis involved one-step dimerization of the precursor, 4-nitro-1-p-methoxybenzyl-5-methyl-1H-imidazole (2), using N-chlorosuccinimide catalyzed by potassium t-butoxide.
| Reference Key |
hosmane2000moleculessynthetic
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|---|---|
| Authors | ;Ramachandra S. Hosmane;Saika Siddiqui |
| Journal | Journal of ethnopharmacology |
| Year | 2000 |
| DOI |
10.3390/50600856
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| URL | |
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