ginecomastia induzida por anti-histamínicos no tratamento da urticária crônica antihistaminic-induced gynecomastia in chronic urticaria treatment

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ID: 153038
2007
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Abstract
Os anti-histamínicos são drogas muito usadas na prática do dermatologista, sendo a primeira escolha no tratamento da urticária crônica. Os efeitos colaterais mais comuns são os relacionados ao sistema nervoso central. A ginecomastia é decorrente de várias causas, entre elas a indução por drogas. Apresenta-se caso de ginecomastia induzida por anti-histamínico H1,em paciente em tratamento de urticária crônica. A investigação laboratorial e radiológica descartou outras causas para a ginecomastia, que involuiu com a retirada da medicação. Objetiva-se discutir os efeitos colaterais dos anti-histamínicos e apresentar caso de ginecomastia induzida por drogas.
Antihistaminic drugs are very commonly used in dermatological practice, and are the first-line therapy to chronic urticaria. The commonest side effects are related to the central nervous system. Gynecomastia, in turn, may be due to a myriad of disorders, including the use of medication. The case of H1 antihistaminic-induced gynecomastia in a patient undergoing chronic urticaria treatment is reported. Radiological and laboratorial investigations discarded other possible causes for the gynecomastia, which disappeared after removal of the medication. Antihistaminic-related side effects, including gynecomastia, are discussed.
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Authors ;Ana Paula Fusel de Ue;Juliana Kida Ikino;Wellington Jesus Furlani;Patrícia Karla de Souza;Osmar Rotta
Journal Theriogenology
Year 2007
DOI
10.1590/S0365-05962007000300007
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962007000300007
Keywords
urticaria histamine antagonists ginecomastia

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