heavy metal hazards of pediatric syrup administration in nigeria: a look at chromium, nickel and manganese

Clicks: 361
ID: 151572
2009
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Star

Ranked #42 of 642 articles by views in archives of biochemistry and biophysics

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 642 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Fifty different pediatric syrups were randomly sampled from patent medicine stores and pharmaceutical shops within Awka (Anambra State, Nigeria) between November 2007 and May 2008. Syrups were ashed before digestion using conc. aqua regia, HCl: HNO3 (3:1). Chromium, nickel and manganese were assayed with AAS 205A. The highest levels of nickel were seen in Magcid suspension (4.13 mg/L) and Gaviron (0.79 mg/L) whereas lowest levels were found in Asco–J vitamin and Jawaron Syrup (0.01 mg/L). About 44.1, 73.6 and 20.6% of the sampled syrups made in Nigeria had non detectable levels of nickel, chromium and manganese respectively. Chromium levels ranged from 0.01 mg/L in Magcid suspension to 0.58 mg/L in emvite. Ferobin and Jawaron Syrup plus had 28.23 and 4.37 mg/L manganese, respectively. With the exception of Cephalexin Syrup, all the imported syrups had non detectable levels of chromium. The level of chromium in Cephalexin Syrup was 0.01 mg/L. About 68.8 and 43.7% of these imported syrups had non-detectable levels of nickel and manganese respectively. Nickel levels ranged from 0.01-0.09 mg/L in the imported syrups. Haemoglobin Syrup showed highest level of manganese of 0.36 mg/L whereas the lowest concentration was 0.02 mg/L in Cadiphen. Taken together the Nigerian made syrup samples had higher concentrations of the studied heavy metals. It is feared that ingestion of these syrups may constitute a significant source of heavy metal exposure to the children and should therefore be considered a public health problem. The public health hazards from ingestion of these syrups should be identified and disclosed by in-depth risk assessment studies.
Reference Key
orisakwe2009internationalheavy Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Orish Ebere Orisakwe;John Kanayochukwu Nduka
Journal archives of biochemistry and biophysics
Year 2009
DOI
10.3390/ijerph6071972
URL
http://www.mdpi.com/1660-4601/6/7/1972/
Keywords
public health chromium pollution nickel nigeriamedicine

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.