medical image of the week: leptomeningeal carcinomatosis

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ID: 151498
2014
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Ranked #10 of 49 articles by views in journal of photochemistry and photobiology b: biology

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Abstract
No abstract available. Article truncated at 150 words. A 65 year old woman with a history of breast cancer presented to the emergency department (ED) with dizziness and disequilibrium, which started a week prior to admission. A year ago, she was diagnosed with locally advanced lobular carcinoma confined to the left breast (Figure 1). She underwent mastectomy followed by chemoradiation including taxol, sunitinib, cyclophosphamide and doxorubicin with remarkable response, and achieved complete remission. In the ED, her neurologic status deteriorated rapidly, she developed tonic-clonic seizures and became unresponsive to verbal and painful stimuli. CT of the head showed no evidence of acute intracranial abnormality or metastatic lesion, however, a brain MRI brain showed contrast enhancement and increased fluid attenuated inversion recovery (FLAIR) signal of the leptomeninges in cranial nerves III, V, VII and VIII as well as cerebellar surface, suggesting meningeal carcinomatosis (Figure 2B and 2C). A lumbar puncture demonstrated malignant cells in the cerebospinal fluid confirming the ...
Reference Key
r2014southwestmedical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Bernardo R;Yun S;Chaudhury A;Maher K;Siddiqi T
Journal journal of photochemistry and photobiology b: biology
Year 2014
DOI
10.13175/swjpcc028-14
URL
Keywords
Breast cancer MRI diagnosis survival seizure polysomnography apnea congestive heart failure periodic breathing critical care first aid intensive care

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