fitness versus fatness and insulin resistance in u.s. adolescents
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2010
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Abstract
Background. The present study examined the relationship between insulin resistance and both
waist circumference and cardiorespiratory fitness in U.S. adolescents. Methods. NHANES assessed a nationally representative sample of U.S. adolescents (12–18 yrs) between 1999–2002. Abdominal adiposity was estimated by waist circumference, overall
adiposity by BMI, and cardiorespiratory fitness (maximal oxygen uptake (VO2max) from a
treadmill exercise test). Insulin resistance was estimated from fasting insulin and glucose using
the homeostatic model assessment method (i.e., HOMA) and was log-transformed.
Results. 1078 adolescents were included in the study. Positive correlations existed between
lnHOMA and waist circumference (r=0.59; r=0.54) for boys and girls, respectively. lnHOMA and VO2max were inversely related in boys (r=−0.29) but not girls (r=−0.06). Gender-specific analyses by BMI category showed that the significant inverse relationship in lnHOMA and VO2max was primarily present in obese boys.
Conclusion. Among adolescents, important gender and BMI differences exist in the relationship
between insulin resistance and fitness. While waist circumference and BMI are important
predictors in all children, fitness appears especially important in obese boys. These findings may
have important implications for gender-specific interventions to prevent adult obesity and
diabetes mellitus.
| Reference Key |
cummings2010journalfitness
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|---|---|
| Authors | ;Doyle M. Cummings;Katrina D. DuBose;Satomi Imai;David N. Collier |
| Journal | chinese chemical letters |
| Year | 2010 |
| DOI |
10.1155/2010/195729
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| URL | |
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