premedication with oral tramadol reduces severity of postoperative shivering after general anesthesia

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ID: 149802
2014
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Abstract
Background: Postanesthetic shivering (PAS) is an accompanying part of general anesthesia with different unpleasant and stressful complications. Considering the importance of proper prevention of PAS in order to reduce its related adverse complications in patients undergoing surgery, in this study, we investigated the effect of orally administrated tramadol in the prevention of this common complication of general anesthesia. Materials and Methods: In this prospective randomized double-blind clinical trial, 80 ASA I and II patients aged 15-70 years, scheduled for elective surgery under general anesthesia, were randomized to intervention (oral tramadol 50 mg) and placebo groups. PAS was evaluated during surgery and in the recovery room, and compared in the two study groups. Results: PAS was seen in 5 patients (12.5%) in the intervention group and 10 patients (25%) in the placebo group (P = 0.12). The prevalence of grade III and IV shivering was 7.5% (3/40) and 25% (10/40) in tramadol and placebo groups, respectively (P = 0.03). Conclusion: The overall prevalence of PAS was not significantly different in the two study groups, but the higher grades of shivering which needed treatment were significantly lower in the tramadol group than in the placebo, and those patients who received tramadol experienced milder form of shivering. It is suggested that higher doses of tramadol would have better anti-shivering as well as analgesic effects. Studying different doses of tramadol would be helpful in this regard.
Reference Key
heidari2014advancedpremedication Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Sayed Morteza Heidari;Mojtaba Rahimi;Hasanali Soltani;Sayed J Hashemi;Shadi Shabahang
Journal microbiological research
Year 2014
DOI
10.4103/2277-9175.125845
URL
http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=64;epage=64;aulast=Heidari
Keywords
oral tramadolmedicinebiology (general)

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