complex underdetermination and the units of clinical translation

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2015
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Abstract

What makes a high-quality biomarker experiment? The success of personalized medicine hinges on the answer to this question. Unfortunately, as many commentators have now emphasized, the quality of most biomarker experiments to date has been quite low. Although the technical side of this problem has received considerable attention, the philosophical issues remain largely unexplored. In this paper, I argue that understanding what constitutes a high-quality biomarker experiment requires some fundamental shifts in how we think about the epistemology, ontology, and methodology of clinical translation.

Reference Key
hey2015theoriacomplex Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Spencer Phillips Hey
Journal central european journal of biology
Year 2015
DOI
10.1387/theoria.12697
URL
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