high performance thin layer chromatographic determination of nifedipine in human serum after liquid-liquid extraction

Clicks: 227
ID: 149268
2012
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #121 of 253 articles by views in greece and rome

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 253 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
A method using HPTLC for quantitation of nifedipine in serum was developed and validated. It includes a liquid-liquid extraction, and carbamazepine as internal standard. Chloroform: ethyl acetate: cyclohexane (19:2:2, v/v/v) was the mobile phase. The method showed good relationship (r = 0.996) (2.00 to 25.00 ng/band, corresponding to 0.02 and 0.25 ng/µL in serum). The % RSD of intra-assay and inter-assay, were between 0.57 and 3.56 and 1.16 to 3.60, respectively. LOD and LOQ were 0.72 and 0.86 ng/band, respectively. The recovery values were between 93 and 102%. Rf for nifedipine and carbamazepine were 0.31 and 0.10, respectively.
Reference Key
mennickent2012qumicahigh Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sigrid Mennickent, Jonathan Contreras, Berta Schulz, Marta de Diego, Mario Vega
Are you one of these authors? Claim your profile
Journal greece and rome
Year 2012
DOI
10.1590/S0100-40422012000200032
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000200032&lng=en&tlng=en
Keywords
quantitative determinationchemistry

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.