infections and ischemic stroke outcome

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ID: 149165
2011
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Abstract
Background. Infections increase the risk of ischemic stroke (IS) and may worsen IS prognosis. Adverse effects of in-hospital infections on stroke outcome were also reported. We aimed to study the prevalence of pre- and poststroke infections and their impact on IS outcome. Methods. We analysed clinical data of 2066 IS patients to assess the effect of pre-stroke and post-stroke infections on IS severity, as well as short-term (up to 30 days) and long-term (90 days) outcome. The independent impact of infections on poor outcome (death, death/dependency) was investigated by use of logistic regression analysis. The effect of antibiotic therapy during hospitalization on the outcome was also assessed. Results. Pre-stroke infections independently predicted worse short-term outcome. In-hospital infections were associated with worse short-term and long-term IS prognosis. Antibacterial treatment during hospitalization did not improve patients' outcome. Conclusions. Prevention of infections may improve IS prognosis. The role of antibiotic therapy after IS requires further investigations.
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grabska2011neurologyinfections Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Katarzyna Grabska;Grazyna Gromadzka;Anna Czlonkowska
Journal Clinical oral investigations
Year 2011
DOI
10.1155/2011/691348
URL
http://dx.doi.org/10.1155/2011/691348
Keywords
neurology diseases of the nervous system

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