uso de probióticos na rinite alérgica probiotics in allergic rhinitis

Clicks: 373
ID: 148431
2011
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Abstract
Probióticos são microrganismos viáveis, usados como suplemento alimentar, normalmente bactérias ácidas lácticas, que podem modificar a composição e/ou a atividade metabólica da microbiota intestinal, modulando o sistema imune de forma que beneficie a saúde do indivíduo. OBJETIVO: Fazer uma revisão sobre o uso de Probióticos (Lactobacillus e Bifidobacterium) na rinite alérgica. MATERIAL E MÉTODO: Foram pesquisados artigos originais no Pubmed. RESULTADOS: Os resultados encontrados indicam que os probióticos, Lactobacillus e Bifidobacterium parecem prevenir as recorrências alérgicas, aliviar a severidade dos sintomas e promover melhora da qualidade de vida dos pacientes com rinite alérgica. Estes efeitos ocorrem devido à modulação do sistema imunológico através da indução da produção de citocinas que promovem uma resposta TH1 dominante em alérgicos, através do efeito da modulação no balanço TH1/TH2. CONCLUSÃO: O uso de bactérias probióticas pode ser uma forma efetiva e segura de prevenção e/ou tratamento de rinite alérgica, mas seu mecanismo exato de ação permanece desconhecido. No entanto, estudos clínicos usando probióticos e intervenção dietética deverão ser o foco de futuras investigações, para permitir um uso mais amplo.
Probiotics are live microorganisms used as supplementary food, usually lactic acid bacteria that can change either the composition and/or the metabolic activities of the gut microbiota modulating the immune system in a way that benefits the person's health. AIM: To review the use of Probiotics (Lactobacillus and Bifidobacterium) in allergic rhinitis patients. MATERIALS AND METHODS: Pubmed original articles were used as data source. RESULTS: Results indicate that probiotics, Lactobacillus and Bifidobacterium appear to prevent allergy recurrences, alleviate the severity of symptoms and improve the quality of life of patients with allergic rhinitis. This happens because of the immune system modulation through the induction of cytokine production which cause a dominant TH1 response in allergic patients by modulating the TH1/TH2 balance effect. CONCLUSION: The use of probiotic bacteria could be an effective and safe way to prevent and/or treat allergic rhinitis, but its underlying mechanisms remain unclear. Therefore, clinical studies using probiotics and dietary intervention should be the focus of future research to enable a more widespread use.
Reference Key
nogueira2011brazilianuso Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Janaina Cândida Rodrigues Nogueira;Maria da Conceição Rodrigues Gonçalves
Journal cardiovascular diabetology
Year 2011
DOI
10.1590/S1808-86942011000100022
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000100022
Keywords
Bifidobacterium rhinitis lactobacillus rinite

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