lymphoid infiltrates in b cell non hodgkin’s lymphoma: comparing nuclear characteristics between lymph node and bone marrow; and evaluating diagnostic features of bone marrow infiltrates in paraffin embedded tissues

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ID: 148251
1997
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Abstract
Distinguishing non Hodgkin’s lymphoma from benign lymphoid aggregates in bone marrow is well recognised to be difficult. Our objective was to evaluate nuclear morphology, and to perform morphometry on benign and neoplastic lymphoid infiltrates, to establish if objective criteria were of value in the diagnosis of neoplasia. By comparing neoplastic infiltrates in bone marrow with infiltrates in lymph nodes, the validity of grading non Hodgkin’s lymphoma on the basis of bone marrow histology alone was assessed. 82 cases of B cell non Hodgkin’s lymphoma (44 low grade and 38 high grade), known to have both lymph node and bone marrow involvement at the time of presentation, were compared with bone marrow trephines containing reactive lymphoid infiltrates.
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deverell1997analyticallymphoid Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Mark H. Deverell;Elizabeth Best;Jonathan R. Salisbury
Journal oriente moderno
Year 1997
DOI
10.1155/1997/696159
URL
http://dx.doi.org/10.1155/1997/696159
Keywords
neoplasms Oncology including cancer and carcinogenscytology tumors

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