current and potential applications of bismuth-based drugs

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ID: 147614
2014
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Abstract
: Bismuth compounds have been used extensively as medicines and in particular for the treatment of gastrointestinal ailments. In addition to bismuth’s well known gastroprotective effects and efficacy in treating H. pylori infection it also has broad anti-microbial, anti-leishmanial and anti-cancer properties. Aspects of the biological chemistry of bismuth are discussed and biomolecular targets associated with bismuth treatment are highlighted. This review strives to provide the reader with an up to date account of bismuth-based drugs currently used to treat patients and discuss potential medicinal applications of bismuth drugs with reference to recent developments in the literature. Ultimately this review aims to encourage original contributions to this exciting and important field.
Reference Key
keogan2014moleculescurrent Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Donal M. Keogan;Darren M. Griffith
Journal Journal of ethnopharmacology
Year 2014
DOI
10.3390/molecules190915258
URL
http://www.mdpi.com/1420-3049/19/9/15258
Keywords
Medicinal Chemistry gastrointestinal bismuth anti-cancerorganic chemistry

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