Úlcera de marjolin associada a ulceração e osteomielite crônicas marjolin's ulcer associated with ulceration and chronic osteomyelitis

Clicks: 311
ID: 146868
2011
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Abstract
Doente do sexo masculino, de 78 anos, portador de uma úlcera venosa crônica na perna esquerda, com cerca de 24 anos de evolução, complicada por carcinoma espinocelular. Após o estadia mento da doença, o tratamento preconizado foi amputação acima do joelho esquerdo. A úlcera de Marjolin é a transformação maligna de uma lesão ulcerosa crônica. Trata-se de um fenômeno relativamente raro. A neoplasia maligna mais frequentemente descrita na literatura é o carcinoma espinocelular, seguido do basalioma, sarcoma e melanoma. A sua patogenia permanece pouco compreendida.
This report describes a 78-year old male patient with a chronic venous ulcer on his left leg for the past 24 years, complicated by a squamous-cell carcinoma. After staging of the disease, the treatment administered was amputation of the leg above the knee. Marjolin's ulcer consists of the malignant transformation of a chronic ulcerative lesion. It is a relatively rare phenomenon. The malignant tumor most commonly described in the literature is squamous cell carcinoma, followed by basal-cell carcinoma, sarcoma and melanoma. The pathogenesis of Marjolin's ulcer remains to be fully clarified.
Reference Key
tavares2011anaislcera Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Ermelindo Tavares;Gonçalo Martinho;José Alberto Dores;Frederico Vera-Cruz;Luís Ferreira
Journal Theriogenology
Year 2011
DOI
10.1590/S0365-05962011000200026
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000200026
Keywords
carcinoma leg ulcer squamous cell

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