sexual dimorphism of stress response and immune/ inflammatory reaction: the corticotropin releasing hormone perspective
Clicks: 181
ID: 145528
1995
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Abstract
This review higlghts key aspects of corticotropin releasing hormone (CRH) biology of potential relevance to the sexual dimorphism of the stress response and immune/inflammatory reaction, and introduces two important new concepts based on the regulatory potential of the human (h) CRH gene: (1) a proposed mechanism to account for the tissue-specific antithetical responses of hCRH gene expression to glucocorticolds, that may also explain the frequently observed antithetical effects of chronic glucocorticoid administration in clinical practice and (2) a heuristic diagram to illustrate the proposed modulation of the stress response and immune/ inflammatory reaction by steroid hormones, from the perspective of the CRH system.
| Reference Key |
vamvakopoulos1995mediatorssexual
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|---|---|
| Authors | ;Nicholas V. Vamvakopoulos |
| Journal | polyhedron |
| Year | 1995 |
| DOI |
10.1155/S0962935195000275
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| URL | |
| Keywords |
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