en bloc pancreaticoduodenectomy for locally advanced right colon cancers

Clicks: 213
ID: 144584
2017
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Ranked #58 of 87 articles by views in Langmuir : the ACS journal of surfaces and colloids

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Abstract
Locally advanced right colon cancer may invade adjacent tissue and organs. Direct invasion of the duodenum and pancreas necessitates an en bloc resection. Previously, this challenging procedure was associated with high morbidity and mortality; however, today, this procedure can be done more safely in experienced centers. The aim of this study is to report our experience on en bloc right colectomy with pancreaticoduodenectomy for locally advanced right colon cancers. Between 2000 and 2012, 5 patients underwent en bloc multivisceral resection. No major morbidities or perioperative mortalities were observed. Median disease-free survival time was 24.5 months and median overall survival time was 42.1 (range: 4.5–70.4) months in our series. One patient lived 70 months after multivisceral resection and underwent cytoreductive surgery and total pelvic exenteration during the follow-up period. In locally advanced right colon tumors, all adhesions should be considered as malign invasion and separation should not be done. The reasonable option for this patient is to perform en bloc pancreaticoduodenectomy and right colectomy. This procedure may result in long-term survival with acceptable morbidity and mortality rates. Multidisciplinary teamwork and multimodality treatment alternatives may improve the results.
Reference Key
aalar2017internationalen Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Cihan Ağalar;Aras Emre Canda;Tarkan Unek;Selman Sokmen
Journal Langmuir : the ACS journal of surfaces and colloids
Year 2017
DOI
10.1155/2017/5179686
URL
http://dx.doi.org/10.1155/2017/5179686
Keywords
neoplasms Oncology including cancer and carcinogens tumors

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