clinical manifestations and management of cryptococcal infection.

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ID: 144284
2005
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Abstract
Cryptococcus neoformans is an important fungal pathogen causing invasive infection, especially of the central nervous system in this era of the HIV/AIDS epidemic. The choice of treatment depends on site(s) of infection and the patient′s immune status. Use of appropriate antifungal agents decreases mortality significantly, but requires continued therapy and long-term maintenance to prevent relapses. The use of liposomal amphotericin B (L Amp B) has overcome some of the difficulties usually found in this setting. The major advantage of these liposomal formulations are faster clearance of C. neoformans [cerebrospinal fluid (CSF) negative] and a reduction in amphotericin toxicity. The majority of clinical efficacy data related to L Amp B are derived from compassionate use studies and case series. Use of liposomal amphotericin has also shown to be a cost effective approach.
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s2005journalclinical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Subramanian S, Mathai D
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Journal international islamic university malaysia engineering journal
Year 2005
DOI
DOI not found
URL
http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2005;volume=51;issue=5;spage=21;epage=26;aulast=Subramanian
Keywords
aids amphotericin b fluconazole cryptococcus meningitismedicine

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