exosomes as mediators of cell-to-cell communication in thyroid disease

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ID: 144023
2020
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Abstract
Exosomes are a type of extracellular vehicle, formed by budding cell membranes, containing proteins, DNA, and RNA. Concentrated cargoes from parent cells are enveloped in exosomes, which are cell specific and may have functions in the recipient cell, reflecting a novel physiological and pathological mechanism in disease development. As a transmitter, exosomes shuttle to different cells or tissues and mediate communications among these organelles. To date, several studies have demonstrated that exosomes play crucial roles in disease pathogenesis and development, such as breast and prostate cancer. However, studies investigating connections between exosomes and thyroid disease are limited. In this review, recent research advances on exosomes in thyroid cancer and Graves’ disease are reviewed. These studies suggest that exosomes are involved in thyroid disease and appear as impressive potentials in thyroid therapeutic areas.
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wang2020internationalexosomes Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Yi Wang;Feng Xu;Jia-Yu Zhong;Xiao Lin;Su-Kang Shan;Bei Guo;Ming-Hui Zheng;Ling-Qing Yuan
Journal zhonghua wei zhong bing ji jiu yi xue
Year 2020
DOI
10.1155/2020/4378345
URL
http://dx.doi.org/10.1155/2020/4378345
Keywords
clinical endocrinology diseases of the endocrine glands

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