multimodality treatment of a massive cervicothoracic lymphatic-venous malformation in a 13-year-old boy
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2017
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Abstract
We report the multi-modality treatment of a massive cervicothoracic lymphatic-venous malformation (LVM) in a 13-year-old boy that was present at birth as a small cervical mass. At four years of age, sclerotherapy significantly reduced the size of the malformation but over subsequent years the mass increased dramatically in size and resulted in a consumptive coagulopathy and limited left shoulder function. Treatment with sildenafil was without effect. The consumptive coagulopathy improved with subcutaneous enoxaparin. A multi-disciplinary team excised part of the mass when he was 11 years old. After surgery, gradual enlargement of the mass and rise in d-dimer prompted treatment with sirolimus. Two sessions of sclerotherapy arrested enlargement of the mass. Multi-modality treatment resulted in a marked reduction of the LVM in the child. However, enlargement of the mass and further treatment is anticipated as a cure has not yet been found.
| Reference Key |
faap2017journalmultimodality
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|---|---|
| Authors | ;Cynthia Reyes, MD, FACS, FAAP;Taylor Parnall, BS;Tania Kraai, MD;Linda Butros, MD;Anna Fabre, MD;Jimmy Windsor, MD;Jason McKee, MD;Gresham Richter, MD |
| Journal | clinical medicine (london, england) |
| Year | 2017 |
| DOI |
10.1016/j.epsc.2017.03.011
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| URL | |
| Keywords | Keywords not found |
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