spontaneous regression of a congenital melanocytic nevus
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ID: 142811
2011
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Abstract
Congenital melanocytic nevus (CMN) may rarely regress which may also be associated with a halo or vitiligo. We describe a 10-year-old girl who presented with CMN on the left leg since birth, which recently started to regress spontaneously with associated depigmentation in the lesion and at a distant site. Dermoscopy performed at different sites of the regressing lesion demonstrated loss of epidermal pigments first followed by loss of dermal pigments. Histopathology and Masson-Fontana stain demonstrated lymphocytic infiltration and loss of pigment production in the regressing area. Immunohistochemistry staining (S100 and HMB-45), however, showed that nevus cells were present in the regressing areas.
| Reference Key |
nath2011indianspontaneous
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|---|---|
| Authors | ;Amiya Kumar Nath;Devinder Mohan Thappa;Nachiappa Ganesh Rajesh |
| Journal | crystallization of organic compounds: an industrial perspective |
| Year | 2011 |
| DOI |
10.4103/0378-6323.82418
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