isolation and antigenic characterization of human immunodeficiency virus (hiv) in brazil isolamento e caracterização antigênica do vírus da imunodeficiência humana (vih/hiv) no brasil

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ID: 142610
1987
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Abstract
A retrovirus infecting a Brazilian AIDS patient was isolated and characterized in terms of its reactivity with sera from individuals infected with human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-2). The Western blot analysis revealed that the Brazilian isolate is very similar to the well characterized HIV-1 strain. The serum of the patient from whom the virus was isolated did not react with the 140 kDa envelope glycoprotein specific for HIV-2.
Um retrovírus foi isolado de um paciente brasileiro com "Síndrome de Imunodeficiência Adquirida" (SIDA/AIDS) e caracterizado em termos de sua reatividade com soros de indivíduos infectados com vírus da imunodeficiência humana dos tipos 1 e 2 (HIV-1 e HIV-2). A análise antigênica por "Western blot" revelou que o isolado brasileiro é bastante similar a uma cepa de HIV-1 bem caracterizada. A identificação do retrovírus como HIV-1 e não HIV-2 é reforçada pelo fato dos anticorpos do paciente do qual foi isolado o vírus não terem reagido com a glicoproteínas de envelope de 140 kDa, específica para HIV-2.
Reference Key
galvo-castro1987memriasisolation Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;B. Galvão-Castro;J. Ivo-dos-Santos;J. C. Couto-Fernandez;V. Bongertz;Dumith Chequer-Bou-Habib;F. S. Sion;O. M. Barth;H. Pereira;M. S. Pereira
Journal kurdistan journal of applied research
Year 1987
DOI
10.1590/S0074-02761987000400001
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000400001
Keywords
human immunodeficiency virus brasil isolation antigens tropical medicinemicrobiology

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