isolation and antigenic characterization of human immunodeficiency virus (hiv) in brazil isolamento e caracterização antigênica do vírus da imunodeficiência humana (vih/hiv) no brasil
isolasi dan karakterisasi antigenik virus imunodefisiensi manusia (hiv) di brasil isolasi dan karakterisasi antigenik virus imunodefisiensi manusia (vih/hiv) di brasil
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Abstract
Um retrovírus foi isolado de um paciente brasileiro com "Síndrome de Imunodeficiência Adquirida" (SIDA/AIDS) e caracterizado em termos de sua reatividade com soros de indivíduos infectados com vírus da imunodeficiência humana dos tipos 1 e 2 (HIV-1 e HIV-2). A análise antigênica por "Western blot" revelou que o isolado brasileiro é bastante similar a uma cepa de HIV-1 bem caracterizada. A identificação do retrovírus como HIV-1 e não HIV-2 é reforçada pelo fato dos anticorpos do paciente do qual foi isolado o vírus não terem reagido com a glicoproteínas de envelope de 140 kDa, específica para HIV-2.
Suatu retrovirus diisolasi dari seorang pasien Brasil dengan "Sindrom Imunodefisiensi Didapat" (AIDS) dan dikarakterisasi berdasarkan reaktivitasnya dengan serum dari individu yang terinfeksi virus imunodefisiensi manusia tipe 1 dan 2 (HIV-1 dan HIV-2). Analisis antigenik melalui "*Western blot*" mengungkapkan bahwa isolat Brasil tersebut sangat mirip dengan galur HIV-1 yang telah terkarakterisasi dengan baik. Identifikasi retrovirus tersebut sebagai HIV-1 dan bukan HIV-2 diperkuat oleh fakta bahwa antibodi dari pasien tempat virus tersebut diisolasi tidak bereaksi dengan glikoprotein selubung 140 kDa yang spesifik untuk HIV-2.
| Reference Key |
galvo-castro1987memriasisolation
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| Authors | ;B. Galvão-Castro;J. Ivo-dos-Santos;J. C. Couto-Fernandez;V. Bongertz;Dumith Chequer-Bou-Habib;F. S. Sion;O. M. Barth;H. Pereira;M. S. Pereira |
| Journal | kurdistan journal of applied research |
| Year | 1987 |
| DOI |
10.1590/S0074-02761987000400001
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| URL | |
| Keywords |
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