antimicrobial susceptibility patterns among escherichia coli urinary isolates from community-onset health care-associated urinary tract infection

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ID: 141380
2014
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Ranked #146 of 246 articles by views in Bioorganic & medicinal chemistry letters

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Abstract
Urinary tract infection (UTI) is traditionally classified as community-acquired (CA) and hospital-acquired (HA). Community-onset health care-associated (HCA) infection is a new category that has gained increasing attention. The study aimed to compare the disk susceptibility of nonrepetitive Escherichia coli urinary isolates from HCA-UTI (n = 100) with that of E. coli isolates from CA-UTI (n = 85) and HA-UTI (n = 106). We found that the susceptibility pattern of HCA-UTI E. coli isolates was similar to that of HA-UTI E. coli isolates, but significantly different from that of CA-UTI E. coli isolates. In particular, the proportion of extended-spectrum β-lactamase-producing isolates was significantly higher in HCA-UTI than that in CA-UTI (30.0% vs. 3.5%, p < 0.001). We recommend that when treating HCA-UTI, it is necessary to take urine cultures for susceptibility testing to guide definite antibiotic therapy.
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huang2014journalantimicrobial Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Ling-Fu Huang;Yi-Chu Lo;Lin-Hui Su;Chin-Lu Chang
Journal Bioorganic & medicinal chemistry letters
Year 2014
DOI
10.1016/j.jfma.2014.01.009
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