modelo experimental ex vivo com bloco pulmonar dividido ex vivo experimental model: split lung block technique
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2011
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Abstract
Modelos de recondicionamento pulmonar ex vivo têm sido avaliados desde sua proposição. Quando são utilizados pulmões humanos descartados para transplante, a grande variabilidade entre os casos pode limitar o desenvolvimento de alguns estudos. No intuito de reduzir esse problema, desenvolvemos uma técnica de separação do bloco pulmonar em direito e esquerdo com posterior reconexão, permitindo que um lado sirva de caso e o outro de controle.
Since they were first established, ex vivo models of lung reconditioning have been evaluated extensively. When rejected donor lungs are used, the great variability among the cases can hinder the progress of such studies. In order to avoid this problem, we developed a technique that consists of separating the lung block into right and left blocks and subsequently reconnecting those two blocks. This technique allows us to have one study lung and one control lung.
Since they were first established, ex vivo models of lung reconditioning have been evaluated extensively. When rejected donor lungs are used, the great variability among the cases can hinder the progress of such studies. In order to avoid this problem, we developed a technique that consists of separating the lung block into right and left blocks and subsequently reconnecting those two blocks. This technique allows us to have one study lung and one control lung.
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mariani2011jornalmodelo
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| Authors | ;Alessandro Wasum Mariani;Israel Lopes de Medeiros;Paulo Manuel Pêgo-Fernandes;Flávio Guimarães Fernandes;Fernando do Valle Unterpertinger;Lucas Matos Fernandes;Mauro Canzian;Fábio Biscegli Jatene |
| Journal | cryobiology |
| Year | 2011 |
| DOI |
10.1590/S1806-37132011000600013
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