expression analysis of cd63 in salivary neutrophils and the increased level of streptococcus mutans in severe early childhood caries
Clicks: 317
ID: 140612
2015
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
30.0
/100
317 views
52 readers
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #30 of 127 articles by views in industrial crops and products
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 127 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Background: Severe early childhood caries (S-ECC) and decay exfoliation filling teeth (def-t) >6 is a destructive disease that afflicts teeth, including maxillary anterior teeth. In Indonesia, the prevalence of this disease is still high, for instance in Semarang 2007, the rate reached 90.5% in urban areas and 95.9% in rural areas for early childhood caries which is caused by Streptococcus mutans (S. mutans). Neutrophils are effector cells of innate immunity which become the main component of the very first line of defense against microbes. Purpose: This study analyzed the effect caused by the change of CD63 expression on the surface of salivary neutrophils and the increased level of S. mutans in S-ECC. Method: This study employs observational analytic and cross sectional approach by using T test analysis technique for forty cases of early childhood that had been divided into two groups, first group of twenty children positively diagnosed as S-ECC and second group of twenty children negatively diagnosed as the control group. The sample’s result of gargling with 1.5% NaCl was used for neutrophils isolation and analysis function of salivary neutrophils phagocytosis by using flow cytometry test, while the sample of saliva was used to isolate S. mutans and calculate the level of S. mutans. Result: The expression of CD63+ salivary neutrophils in S-ECC was lower (2.32% ± 0.57) than in caries-free (2.67% ± 0.46), while the level of S. mutans showed that the level was not higher than in S-ECC (9.78 ± 2.22)x105 CFU/ml compared to in caries-free (5.13 ± 1.86)x105 CFU/ml. Conclusion: The low expression of CD63 in salivary neutrophils can lead to the increased level of S. mutans in S-ECC.
| Reference Key |
luthfi2015dentalexpression
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Muhammad Luthfi |
| Journal | industrial crops and products |
| Year | 2015 |
| DOI |
10.20473/j.djmkg.v48.i2.p89-93
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.