qualitative and quantitative lymphoscintigraphy in the evaluation of lower limbs lymphedema

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ID: 140499
2005
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Abstract
The purpose of this study was to prove the efficiency of qualitative and quantitative lymphoscintigraphy in the diagnosis of the lower extremity lymphedema. Seventy-seven patients had been studied, most of then (85.7%) were female. Patients’ ages ranged from 18 to 82 years. All patients underwent a bilateral lymphoscintigraphy. Images were recorded with a dual-detector instrument in the whole-body scanning mode. Feet and inguinal static views were acquired within 15 minutes and three hours after radiopharmaceutical injection. Two nuclear doctors evaluated the lymphoscintigrams qualitatively. Quantitative studies of the radiopharmaceutical absorption and the lymph node chain uptake were also obtained. Of the 154 evaluated members, 21.44% (n = 33) were classified as normal, 61.68% (n = 95) as mildly altered and 16.88% (n = 26) much altered. Quantitation of lymphatic chain uptake may be a more sensitive approach to the diagnosis of lymphatic impairment than the qualitative analysis.
O objetivo do estudo foi comprovar a eficiência da linfocintilografia qualitativa e quantitativa no diagnóstico e na classificação da gravidade do linfedema de membros inferiores. Foram estudados 77 pacientes, sendo 66 (85,7%) do sexo feminino, na faixa etária entre 18 e 82 anos. Todos os pacientes foram submetidos a uma linfocintilografia bilateral, com um equipamento de dois detectores, na qual se adquiriu imagens dos pés, da região inguinal e uma varredura dos membros, após 15 minutos e três horas da injeção do radiofármaco. Os exames foram avaliados qualitativamente por 2 médicos nucleares. Também foram feitos estudos quantitativos da absorção do radiofármaco e da captação em cadeia inguinal. Dos 154 membros avaliados classificaram-se como normais 21,44% (n=33), pouco alterados 61,68% (n=95) e muito alterados 16,88% (n=26). A quantificação da captação da cadeia linfática pode ser um método mais sensível para o diagnóstico do linfedema em relação à análise qualitativa.
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dalia2005brazilianqualitative Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Roberta Maria Dalia;Gláucia Ribeiro P. Martins;Rodolfo Barbosa;Carla Flávia de Lima;Cristiano Ferrari Siqueira
Journal current drug delivery
Year 2005
DOI
10.1590/S1516-89132005000700023
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700023
Keywords
lymphedema dextran radiopharmaceuticalbiotechnology

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