recent transmission of drug-resistant mycobacterium tuberculosis in a prison population in southern brazil
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Abstract
ABSTRACT We conducted a cross-sectional, retrospective study, characterized by classical and molecular epidemiology, involving M. tuberculosis isolates from a regional prison in southern Brazil. Between January of 2011 and August of 2014, 379 prisoners underwent sputum smear microscopy and culture; 53 (13.9%) were diagnosed with active tuberculosis. Of those, 8 (22.9%) presented with isoniazid-resistant tuberculosis. Strain genotyping was carried out by 15-locus mycobacterial interspersed repetitive unit-variable-number tandem-repeat analysis; 68.6% of the patients were distributed into five clusters, and 87.5% of the resistant cases were in the same cluster. The frequency of drug-resistant tuberculosis cases and the rate of recent transmission were high. Our data suggest the need to implement an effective tuberculosis control program within the prison system.
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| Authors | ;Ana Julia Reis;Simone Maria Martini de David;Luciana de Souza Nunes;Andreia Rosane de Moura Valim;Lia Gonçalves Possuelo |
| Journal | cryobiology |
| Year | Year not found |
| DOI |
10.1590/S1806-37562016000000023
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