in vitro and in vivo sers biosensing for disease diagnosis

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ID: 138000
2018
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Abstract
For many disease states, positive outcomes are directly linked to early diagnosis, where therapeutic intervention would be most effective. Recently, trends in disease diagnosis have focused on the development of label-free sensing techniques that are sensitive to low analyte concentrations found in the physiological environment. Surface-enhanced Raman spectroscopy (SERS) is a powerful vibrational spectroscopy that allows for label-free, highly sensitive, and selective detection of analytes through the amplification of localized electric fields on the surface of a plasmonic material when excited with monochromatic light. This results in enhancement of the Raman scattering signal, which allows for the detection of low concentration analytes, giving rise to the use of SERS as a diagnostic tool for disease. Here, we present a review of recent developments in the field of in vivo and in vitro SERS biosensing for a range of disease states including neurological disease, diabetes, cardiovascular disease, cancer, and viral disease.
Reference Key
moore2018biosensorsin Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;T. Joshua Moore;Amber S. Moody;Taylor D. Payne;Grace M. Sarabia;Alyssa R. Daniel;Bhavya Sharma
Journal journal of human evolution
Year 2018
DOI
10.3390/bios8020046
URL
http://www.mdpi.com/2079-6374/8/2/46
Keywords
Cancer Diabetes sers cardiovascular disease diagnostics neurological disease biosensing

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