evaluation of the purified fraction of wilbrandia (c. f. ) verticillata for antitumour activity
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ID: 137307
1991
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Abstract
Cucurbatacins are known to produce cytotoxic and anticancer activities. Two novel norcucurbitacin glucosides (Wvl and Wv2) have recently been isolated from a purified fraction obtained from the rhizome of Wilbrandia verticillata. The present study evaluates the cytotoxic and anti-tumour activities of the norcucurbitacins. We have found a regular cytotoxicity in KB cells (Cy50 = 12µg/ml) as well as a significant inhibition in the Walker 256 carcinosarcoma growth (approximately 75%).
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| Authors | ;V. S. N. Rao;F. R. C. Almeida;A. P. Moraes;J. V. Silva;S. C. Nascimento;M. O. Moraes |
| Journal | kurdistan journal of applied research |
| Year | 1991 |
| DOI |
10.1590/S0074-02761991000600012
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