performance of bvblue rapid test in detecting bacterial vaginosis among women in mysore, india

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ID: 135045
2014
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Abstract
Bacterial vaginosis (BV) is the most common cause of abnormal vaginal discharge in reproductive age women. It is associated with increased susceptibility to HIV/STI and adverse birth outcomes. Diagnosis of BV in resource-poor settings like India is challenging. With little laboratory infrastructure there is a need for objective point-of-care diagnostic tests. Vaginal swabs were collected from women 18 years and older, with a vaginal pH > 4.5 attending a reproductive health clinic. BV was diagnosed with Amsel’s criteria, Nugent scores, and the OSOM BVBlue test. Study personnel were blinded to test results. There were 347 participants enrolled between August 2009 and January 2010. BV prevalence was 45.1% (95% confidence interval (CI): 41.5%–52.8%) according to Nugent score. When compared with Nugent score, the sensitivity, specificity, positive predictive value, negative predictive value for Amsel’s criteria and BVBlue were 61.9%, 88.3%, 81.5%, 73.7% and 38.1%, 92.7%, 82.1%, 63.9%, respectively. Combined with a “whiff” test, the performance of BVBlue increased sensitivity to 64.4% and negative predictive value to 73.8%. Despite the good specificity, poor sensitivity limits the usefulness of the BVBlue as a screening test in this population. There is a need to examine the usefulness of this test in other Indian populations.
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madhivanan2014infectiousperformance Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Purnima Madhivanan;Karl Krupp;Tan Li;Kavitha Ravi;Julia Selezneva;Vijaya Srinivas;Anjali Arun;Jeffrey D. Klausner
Journal rare earth coordination chemistry: fundamentals and applications
Year 2014
DOI
10.1155/2014/908313
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