effect of microwave irradiation on the condensation of 6-substituted 3-formylchromones with some five-membered heterocyclic compounds

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2000
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Abstract
Different types of 3-substituted 4H-4-oxobenzopyrans were prepared by microwave irradiation as well as by a classical method. The beneficial effect of microwave irradiation on the aldol condensation of 3-formylchromones with 2-imino-1-methylimidazolidine-4-one (creatinine), 2-thioxoimidazolidine-4-one (thiohydantoin) and 2-ethyl-2-thioxothiazolidin-4-one (3-ethylrhodanine) in different reaction media is described. Our results show that the effect of microwave irradiation on the reactions studied was a shortening of the reaction times and a smooth increase in the yields. The subsequent reactions of the product with some nucleophiles are discussed. The structure of the products was proven by elemental analysis, IR and NMR spectra.
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Authors ;Nada Pronayova;Tibor Liptay;Dusan Loos;Renata Gasparova;Margita Lacova
Journal Journal of ethnopharmacology
Year 2000
DOI
10.3390/50200167
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