association of inflammatory and oxidative stress markers with metabolic syndrome in asian indians in india
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ID: 133514
2011
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Abstract
Metabolic syndrome (MetS) is a primary risk factor for cardiovascular disease and is associated with a proinflammatory state. Here, we assessed the contribution of inflammatory and oxidative stress markers towards prediction of MetS. A total of 2316 individuals were recruited in Phase I of the Indian Atherosclerosis Research Study (IARS). Modified ATPIII guidelines were used for classification of subjects with MetS. Among the inflammatory and oxidative stress markers studied, levels of hsCRP (P<.0001), Neopterin (P=.036), and oxLDL (P<.0001) were significantly higher among subjects with MetS. Among the markers we tested, oxLDL stood out as a robust predictor of MetS in the IARS population (OR 4.956 95% CI 2.504–9.810; P<.0001) followed by hsCRP (OR 1.324 95% CI 1.070–1.638; P=.010). In conclusion, oxLDL is a candidate predictor for MetS in the Asian Indian population.
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| Reference Key |
rao2011cardiologyassociation
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|---|---|
| Authors | ;Veena S. Rao;Radhika K. Nagaraj;Sridhara Hebbagodi;Natesha B. Kadarinarasimhiah;Vijay V. Kakkar |
| Journal | acta crystallographica section c, structural chemistry |
| Year | 2011 |
| DOI |
10.4061/2011/295976
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| URL | |
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