withania somnifera improves semen quality in stress-related male fertility

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ID: 133079
2011
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Abstract
Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study to understand the role of stress in male infertility, and to test the ability of W. somnifera to combat stress and treat male infertility. We selected normozoospermic but infertile individuals (N = 60), further categorized in three groups: normozoospermic heavy smokers (N = 20), normozoospermics under psychological stress (N = 20) and normozoospermics with infertility of unknown etiology (N = 20). Normozoospermic fertile men (N = 60) were recruited as controls. The subjects were given root powder of W. somnifera at a rate of 5 g/day for 3 months. Measuring various biochemical and stress parameters before and after treatment, suggested a definite role of stress in male infertility and the ability of W. somnifera to treat stress-related infertility. Treatment resulted in a decrease in stress, improved the level of anti-oxidants and improved overall semen quality in a significant number of individuals. The treatment resulted in pregnancy in the partners of 14% of the patients.
Reference Key
mahdi2011evidence-basedwithania Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Abbas Ali Mahdi;Kamla Kant Shukla;Mohammad Kaleem Ahmad;Singh Rajender;Satya Narain Shankhwar;Vishwajeet Singh;Deepansh Dalela
Journal ACS applied materials & interfaces
Year 2011
DOI
10.1093/ecam/nep138
URL
http://dx.doi.org/10.1093/ecam/nep138
Keywords
Other systems of medicine

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