method development and validation of metformin hydrochloride in tablet dosage form
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ID: 132171
2011
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Abstract
A simple, reproducible and efficient method for the determination of metformin hydrochloride (MET) was developed and validated. The analysis complied with Beer's law in the concentration range of 8-13 μg/mL at 233 nm for MET. In our study the validation of analytical method for determination of MET by UV in tablets formulation was performed in accordance the parameters including-system suitability, specificity, limit of quantification, limit of detection, linearity of response, accuracy, precision (reproducibility & repeatability), robustness (change of wave length±2 nm).
| Reference Key |
mishra2011e-journalmethod
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|---|---|
| Authors | ;Kaushelendra Mishra;Himesh Soni;Govind Nayak;Sita Sharan Patel;A. K. Singhai |
| Journal | Journal of pharmaceutical and biomedical analysis |
| Year | 2011 |
| DOI |
10.1155/2011/768014
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| URL | |
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