the role of micrornas in aβ deposition and tau phosphorylation in alzheimer’s disease

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2017
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Abstract
Alzheimer’s disease (AD), with main clinical features of progressive impairment in cognitive and behavioral functions, is the most common degenerative disease of the central nervous system. Recent evidence showed that microRNAs (miRNAs) played important roles in the pathological progression of AD. In this article, we reviewed the promising role of miRNAs in both Aβ deposition and Tau phosphorylation, two key pathological characters in the pathological progression of AD, which might be helpful for the understanding of pathogenesis and the development of new strategies of clinical diagnosis and treatment of AD.
Reference Key
zhao2017frontiersthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Juanjuan Zhao;Dongxu Yue;Ya Zhou;Li Jia;Hairong Wang;Mengmeng Guo;Hualin Xu;Chao Chen;Jidong Zhang;Lin Xu
Journal journal of photochemistry and photobiology a: chemistry
Year 2017
DOI
10.3389/fneur.2017.00342
URL
http://journal.frontiersin.org/article/10.3389/fneur.2017.00342/full
Keywords
alzheimer’s disease pd-1 tgf-β micrornas treg cells diseases of the nervous system toxoplasma gondiimicrobiology

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