efficient microwave-assisted synthesis of 5-deazaflavine derivatives
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2010
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Abstract
A series of pyrimido[4,5-b]quinolines (5-deazaflavines), were synthesized by microwave assisted intramolecular cyclization. The N4-substituted-2,4-diamino-6-chloro-pyrimidine-5-carbaldehydes, were prepared by selective monoamination of 2-amino-4,6-dichloropyrimidine-5-carbaldehyde with aliphatic and aromatic amines.
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| Authors | ;Justo Cobo;José M. de la Torre;Manuel Nogueras;Jairo Quiroga;Luis Gabriel López;Dency José Pacheco;Jorge Trilleras |
| Journal | Journal of ethnopharmacology |
| Year | 2010 |
| DOI |
10.3390/molecules15107227
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