elevated middle cerebral artery peak systolic velocity in a nonanemic fetus with alpha-thalassemia trait

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ID: 130906
2009
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Abstract
Background. Elevated middle cerebral artery peak systolic velocity (MCA-PSV) has been reported in nonanemic fetuses following fetal transfusion, and has been attributed to a major population of red blood cells (RBCs) with an adult mean corpuscular volume (MCV) in the fetal circulation. Reported here is an analogous case of elevated MCA-PSV with a normal fetal hematocrit and relative fetal microcytosis due to fetal α-thalassemia trait. Case. Ultrasound findings concerning for early hydrops prompted measurement of MCA-PSV, which was elevated. Cordocentesis revealed fetal microcytosis with a normal hematocrit which proved to be due to fetal α-thalassemia trait inherited from the mother. Conclusion. This case provides another example of elevated MCA-PSV with normal hematocrit and microcytosis, here due to fetal α-thalassemia trait. This finding provides support for the observation that MCA-PSV may be influenced by hematological indices other than the fetal hematocrit.
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heyborne2009obstetricselevated Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Kent Heyborne
Journal vìsnik nacìonalʹnogo avìacìjnogo unìversitetu
Year 2009
DOI
10.1155/2009/819380
URL
http://dx.doi.org/10.1155/2009/819380
Keywords
gynecology and obstetrics

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