one-pot synthesis of 2,4,5-tri-substituted-1h-imidazoles promoted by trichloromelamine

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2013
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Abstract
2,4,5-Trisubstituted imidazoles have many pharmaceutical properties and can be prepared via reaction of 1, 2-diketones with aldehydes in the presence of an acidic catalyst. In this work, we have prepared 2,4,5-trisubstituted imidazoles in the presence of trichloromelamine as a source of positive chlorine. Short reaction times, high yield, simplicity of operation and easy work-up are some advantages of this method.
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Authors ;BiBi Fatemeh Mirjalili;Abdolhamid Bamoniri;Najmeh Mohaghegh
Journal proceedings - 2018 4th international conference on computing, engineering, and design, icced 2018
Year 2013
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