hematologycal, biochemical, urinary and histopathological changes in natural intoxication in bovine by bracken fern (pteridium aquilinum) (l.) kühn/
alterações hematológicas, bioquímicas, urinárias e histopatológicas na intoxicação natural em bovinos pela samambaia pteridium aquilnum (l.) kühn

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ID: 130504
2005
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Abstract
Enzootic hematuria is a cronic disease of cows clinically characterized by intermittent hematuria that can be caused by bracken fern (Pteridium aquilinum) and the papilomatosis virus. We describe the clinical and laboratorial abnormalities observed during period of 6 months in naturally affect cows extensively raised in the north region of Paraná State. The animals had low concentrations of total calcium, with normal levels phosphorus and magnesium. Fractional excretion of calcium and phosphorus were increased. Metaplasia and hyperplasia in the epithelium as well as papilomas, hemangiomas, and transitional cell carcinomas were observed histopathologically in the urinary bladder. We were unable to demonstrate any viral presence by imunnohistochemistry and polymerase chain reaction (PCR) of paraffin blocks.

A hematúria enzoótica é uma doença crônica dos bovinos caracterizada clinicamente por hematúria intermitente que pode ser causada pela samambaia (Pteridium aquilinum) e o vírus da papilomatose. Por meio deste estudo verificamos as alterações clínico-laboratoriais em bovinos, mestiços, fêmeas, naturalmente intoxicados pela samambaia, em propriedades rurais de criação extensiva na região norte do Paraná, durante o período de 6 meses. Os resultados mostraram baixo nível plasmático de cálcio, níveis plasmáticos normais para fósforo e magnésio, aumento da excreção urinária fracionada de cálcio e fósforo. Histopatologicamente foram observadas alterações neoplásicas como papiloma, hemangioma e carcinoma de células transicionais além de metaplasia e hiperplasia na bexiga. Provas de imuno-histoquimica e reação em cadeia pela polimerase (PCR) de cortes parafinados mostraram resultado negativo para o agente viral.

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sandini2005semina:hematologycal, Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Itacir Eloi Sandini;Werner Okano;João Pessoa Araújo Jr.;Ana Paula F. R. L. Bracarense;Mara Regina Stipp Balarin;Antônio Carlos Faria dos Reis;Margarete Kimie Falbo
Journal frontiers in neuroendocrinology
Year 2005
DOI
10.5433/1679-0359.2005v26n4p547
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