insulin-like growth factor-binding proteins of teleost fishes
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ID: 130444
2018
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Abstract
The insulin-like growth factor (Igf) binding protein (Igfbp) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the Igfbps of teleost fishes, where genome duplication events have diversified gene repertoire, function, and physiological regulation—with six core Igfbps expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost Igfbp evolution, function, and expression-level regulation, we highlight gaps in our understanding and promising areas for future work.
| Reference Key |
serrana2018frontiersinsulin-like
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|---|---|
| Authors | ;Daniel Garcia de la Serrana;Daniel J. Macqueen |
| Journal | aip advances |
| Year | 2018 |
| DOI |
10.3389/fendo.2018.00080
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| URL | |
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