the intriguing occurrence of acute myeloid leukemia in a case of acute lymphoblastic leukemia:report of two cases

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ID: 130051
2020
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Abstract
The aim of this study is to study the two cases of acute lymphoblastic leukemia (ALL) who relapsed as acute myeloid leukemia (AML). Presented here are reports of two cases of pediatric ALL who developed change of lineage to AML at relapse. This change in phenotype, which involves the conversion of one phenotype to other phenotype during the course of disease or at relapse is a rare phenomenon rarely described in literature. The immunophenotypic and molecular findings are described. The present study emphasizes the need of immunophenotyping and molecular workup at relapse. Also adds to the repertoire of the published literature on this rare entity.
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Authors ;Manasi Chetan Mundada;Faiq Ahmed;Mohan Krishna Pasam;Sudha Murthy;A Santa;Veerendra Patil
Journal journal of applied hematology
Year 2020
DOI
10.4103/joah.joah_64_19
URL
http://www.jahjournal.org/article.asp?issn=1658-5127;year=2020;volume=11;issue=1;spage=21;epage=24;aulast=Mundada
Keywords
acute myeloid leukemia acute lymphoblastic leukemia immunophenotyping

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