antinociceptive activity of methanol extract of spilanthes paniculata linn

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ID: 129915
2014
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Abstract
Spilanthes paniculata Linn. (Asteraceae) is a well-known plant for its folklore use in toothache and tlıroat infection. The methanol extract of S. paniculata was investigated for if s probable antinociceptive activity by hot plate, acetic acid-induced writhing and fonnalin test. The extract at the doses of 250 and 500 mg/kg body weight showed significant (p<0.001) and dose-dependent antinociceptive activity in ali tlıree models used. Tlıis indicates the existence of both Central and peripheral meclıanisms of antinociceptive action of the extract. Ali the experimental results suggest that the methanol extract of S. paniculata contains constituents lıaving antinociceptive properties and support its popular folkloric uses in the management of pain
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das2014turkishantinociceptive Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Biplab Kumar DAS;Kaysar AHMED;Azim UDDIN;Rajib BHATTACHARJEE;Md. Mamun AL-AMIN
Journal petroleum exploration and development
Year 2014
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