single-molecule characterization of extrinsic transcription termination by sen1 helicase
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ID: 129892
2019
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Abstract
Yeast’s Sen1 helicase is involved in the suppression of antisense transcription from bidirectional eukaryotic promoters. Here authors develop and utilize a quantitative single-molecule assay reporting on the kinetics of extrinsic eukaryotic transcription termination by the Sen1 helicase and a reaction intermediate in which the Pol II transcription bubble appears half-rewound.
| Reference Key |
wang2019naturesingle-molecule
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|---|---|
| Authors | ;S. Wang;Z. Han;D. Libri;O. Porrua;T. R. Strick |
| Journal | educacao e sociedade |
| Year | 2019 |
| DOI |
10.1038/s41467-019-09560-9
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